After a ruinous alchemy experiment destroys their bodies, Alphonse and Edric Elric seek the Philosopher's Stone, which may repair the damage. But the prize remains elusive, and the brothers must rely on new allies as they combat dangerous foes. The Elrics meet Father, the creator of the deadly Homunculi, whose power continues to grow. They also encounter Gen. Olivier Armstrong, the intrepid leader of the elite warriors of fortress Briggs.