Ten-year-old science whiz Jimmy Neutron (voiced by Debi Derryberry) loves to invent contraptions, and although he begins with the best of intentions, he usually winds up having to invent another gizmo to undo the damage wrought by the first one upon his hometown of Retroville. Jimmy is abetted in his grandiose schemes by Goddard, his robotic pooch, and an ensemble of quirky friends, including asthmatic Carl, energetic Sheen and brainiac Cindy.